UC Professor Advances Life Saving Research

Dr Rupak Banerjee of CEAS is advancing cardiovascular health improvements.

Date: January 20, 2011

By: Kelley Ujvary



Day in and day out, researchers at UC are doing extraordinary things to enhance the quality of life and provide medical breakthroughs.  One of our UC faculty members is working on a new research project that could improve cardiovascular diagnostics and enhance treatment of cardiovascular dysfunction.

Rupak Banerjee, PhD, is an associate professor of mechanical engineering here at UC out of the College of Engineering and Applied Sciences (CEAS).  Banerjee has been involved in over thirty scholarly research projects and has been awarded over two million dollars to carry out these projects.  One of his current projects with the  Cincinnati VA Medical Center has been the highest amount of direct cost awarded to him and his team totaling close to $600,000. 

Banerjee, in collaboration with UC cardiologists Dr. Mohamed Effat, Dr. Tarek Helmy, Dr. Imran Arif andDr. Massoud  Leesar, has been working to evaluate blockages that occur in the cardiac blood vessels in hopes of providing a more efficient diagnostic for heart-attack patients. 

The research team is using data from a sensor wire in combination with novel parameters to assess the severity of blockages in large arteries of the heart.  The team is broadening its research to evaluate use of this new diagnostic tool in smaller vessels of the heart where the disease may also be present.


Student assessing the placement of the diagnostic guidewire in the model artery.

When asked what promise this research could contribute to other areas, Banerjee said “the diagnostic parameters have wider application and can be used in other cardiovascular and peripheral vascular systems”. All in all, they are looking for a better outcome for all patients with heart disease, at the VA hospital and institutions worldwide.   

The future of this research is to provide improved determination of the cut-off values for these parameters. “Eventually, we hope that these diagnostic parameters can be used during Cath Lab procedures and become the standard of care.” 



Left: Pressure and flow pulse during coronary intervention.                        Right: Lesion assessment of stenosed artery using quantitative coronary angiography (QCA).


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