Bioinformatics

Headshot of Rupak K. Banerjee

Rupak K. Banerjee

Professor, Mechanical Engineering , CEAS - Mechanical Eng

593 Rhodes Hall

513-556-2124

Headshot of Amit Bhattacharya

Amit Bhattacharya

Professor , COM EH Indstr Hygiene Bhattacharya Lab

138 Kettering Lab Complex

513-558-0503

BRIEF BIOGRAPHICAL SKETCH

Dr. Amit Bhattacharya holds a Ph.D. degree in biomedical/mechanical engineering and a M.S. in fluid mechanics/heat transfer, both from the University of Kentucky in Lexington, Kentucky, U.S.A.  He is a tenured Professor of Environmental Health & have also a professor in Biomedical Engineering & Mechanical Engineering at the University of Cincinnati, Cincinnati, Ohio, U.S.A.  He is the founding Director of the Biomechanics‑Ergonomics Research Laboratories of the Department of Environmental Health. He is also the founding director of the Occupational Ergonomics/Safety graduate education program and the Pilot Research Training program sponsored by the National Institute for Occupational Safety and Health (NIOSH) and housed in the Department of Environmental Health within  college of medicine of the University of Cincinnati.  His recent research activities include  topics of gene-environment interaction and its impact on human neuromuscular system and application of Nano-sensors/BIOMEMS technology for early detection of neurodegenerative  and degenerative skeletal disorders. Over the years, Dr. Bhattacharya’s  research at the University of Cincinnati has been sponsored by federal agencies and private organizations (cumulative funding as P.I. and Co-Investigator: ~$29.0 million). Dr. Bhattacharya  has made significant contributions in the areas of biomechanics of slips/falls in the workplace, heat stress, occupational biomechanics of repetitive trauma, work station design, physiological/biomechanical effects of external vibration on animals and humans, therapeutic aspects of whole‑body vibration, development of countermeasures for cardiovascular deconditioning resulting from weightlessness, and  the development of noninvasive, sensitive techniques for the quantification of postural imbalance as an indicator of neurotoxicity and identification of preclinical biomechanical parameters of osteoarthritis and osteoporosis.  His research in the area of noninvasive quantification of postural balance for use in detecting chemical toxicity received national recognition when he was invited by the National Institute of Environmental Health Sciences (NIEHS) to present a hands‑on demonstration of this technique during National Medical Research Day at the U.S. House of Representatives and Earth‑Tech Show (both in Washington, D.C.).  Dr. Bhattacharya serves on the editorial board of the Journal of Occupational Ergonomics and was Chairperson of the Safety and Occupational Health Study Section for the National Institute for Occupational Safety and Health (NIOSH). He is  frequently invited to serve as ad hoc member on a variety of scientific review panels organized by U.S. National Academies of Sciences & Engineering, National Institute of Health (NIH), NIOSH, CDC  and international organizations.  Dr. Bhattacharya has been active as an ergonomic/biomechanics consultant to various private industries as well as governmental agencies such as NIOSH and the National Aeronautics and Space Administration (NASA).  He is a Fellow of the Biomedical Engineering Society & Charter member of the National Academy of Inventors.  Also, he is a full member of the, Human Factors & Ergonomic Society, and the American Industrial Hygiene Association.

Amit Bhattacharya’s current Translational Research activities resulting in a Medical Device   and a start up Biomedical company

Dr. Bhattacharya’s current research activities include:  1) impact of environmental toxicants (e.g. Mn) on human neuromuscular system and susceptibility of developing  degenerative skeletal disorder (e.g. Pb induced osteoporosis),&nb
Headshot of Long (Jason) Lu

Long (Jason) Lu

Associate Professor , COM Pediatrics CCHMC Aff Faculty

Childrens Hospital Bldg R

513-636-8720

Headshot of Jaroslaw Meller

Jaroslaw Meller

Graduate Program Director and Associate Professor , COM EH Bio Meller Lab

316 Kettering Lab Complex

513-558-1958

Building upon broad interdisciplinary training in molecular modeling, computational chemistry, and bioinformatics, Dr. Meller has been pursuing research at the intersection of computational genomics and biomedicine. Dr. Meller has a primary appointment in the Department of Environmental Health, University of Cincinnati College of Medicine, and joint/secondary appointments in the Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, and the School of Electrical Engineering and Computing Systems, University of Cincinnati College of Engineering and Applied Sciences. Dr. Meller has published over 70 original research articles with over 2,500 citations and ISI Web of Science H-index of 30. See professional profiles at http://scholar.google.com/citations?user=vQguoK4AAAAJ&hl=en and http://www.researcherid.com/rid/A-1971-2011 .

Dr. Meller and his group have developed a number of successful methods for the prediction of protein structure, protein-protein interactions and functional hot spots in proteins (Adamczak et al., 2004, 2005; Wagner et al., 2005; Porollo and Meller, 2007, 2010; Adamczak et al., 2011; Phatak et al., 2011). Several web servers developed by the group, including Sable, Sppider, Minnou and Polyview have widely been used, with a total of over 900,000 submissions from more than 30,000 users in many countries. For the development of successful prediction, modeling and visualization tools for structural bioinformatics and functional genomics, Dr. Meller received Ohio Cyber-infrastructure Experimental & Application Research Award. Dr. Meller has also been active in the development and applications of methods for knowledge extraction from high dimensional genomic data (Sinha and Meller, 2008; Shinde et al., 2010; Huang et al., 2012).

Benefiting from a strong emphasis on team science at the University of Cincinnati and Cincinnati Children’s Hospital Medical Center, Dr. Meller and his group have also been involved in many collaborative projects with direct medical relevance. Examples of such interdisciplinary efforts include sequencing and annotation of human pathogens, identification of markers associated with disease subtypes in cancer and autoimmunity, modeling of signal transduction pathways in differentiation and development, developing inhibitors of critical protein-protein interactions in autophagy, bone marrow transplants, and pathogen-host interactions.

Dr. Meller has been broadly involved in quantitative and computational training efforts within UC College of Medicine and College of Engineering and Applied Sciences, leading several inter-departmental and inter-collegiate initiatives in this regard. Dr. Meller serves as the Director of the newly created PhD program in Biomedical Informatics at UC, co-director of the Biomedical Informatics Graduate Certificate Program, and has been involved in several informatics and quantitative training efforts at UC College of Medicine, including T32 Advanced Multidisciplinary Training Program for Systems Biology and T32 Gene-Environment Interactions Training Grant. In addition, Dr. Meller is the co-director of the Bioinformatics Core for the Center of Environmental Genetics at the University of Cincinnati. He also serves as the director of Protein Informatics Core at Cincinnati Children’s Hospital Medical Center.
Headshot of Marepalli B. Rao

Marepalli B. Rao

Professor , COM EH CGI Rao Lab

247 Kettering Lab Complex

513-558-3602