Professor , CEAS - Biomedical Eng
501E Engineering Research Cntr
Associate Professor , CEAS - Biomedical Eng
850 Engineering Research Cntr
Asst Professor , CEAS - Elec Eng & Computer Science
840 Engineering Research Cntr
While at UCLA, Esfandiari also conducted research for the California Nano-System Institution (CNSI), and the Orthopedic Surgery Laboratory. During her academic training, Esfandiari has spent time giving back by leading and training graduate and undergraduate students in conducting research and experiments. Besides her academic practice, she has 4 years of industrial experience at Applied Medical Co and Honeywell Inc.
Dr. Esfandiari has a multidisciplinary research background in development of Microelectromechanical Systems (MEMS) for studying cell mechanics, nano-surface chemistry and development of molecular biosensors. At University of Cincinnati, she is leading the Integrative BioSensing Laboratory with the main focus on design and development of miniaturized biosensors and bio-platforms for point-of-care (POC) medical diagnostics, preventive and therapeutic medicine.
Peter J. Stern Professor & Chair , COM Orthopaedic Surgery
5508 Medical Sciences Building
Michael T. Archdeacon is a Peter J. Stern Professor and Chairman of the Department of Orthopaedic Surgery at the University of Cincinnati Academic Health Center. He serves as the Medical Director of Operative Services and Director of the Division of Musculoskeletal Traumatology at the University of Cincinnati Medical Center. He is Board Certified by the American Board of Orthopaedic Surgery and specializes in difficult fracture care.
Dr. Archdeacon attended Tulane University School of Engineering and obtained his BS in Biomedical Engineering. He then attended the Ohio State University College of Medicine where he received his M.D. He obtained a M.S. in Biomedical Engineering at the Ohio State University College before he completed a General Surgery Internship and an Allen Orthopaedic Surgical Research Fellowship. After completing his residency training at Case Western Reserve University School of Medicine he obtained fellowship training in Orthopaedic Traumatology at Tampa General Hospital.
Dr. Archdeacon is currently serving on the OTA Board of Directors, the Mid-America Orthopaedic Association-Finance Committee as well as the Executive Board of the Ohio Orthopaedic Society as the Treasurer Elect. He currently has more than fifty peer-reviewed publications and book chapters.
Dr. Archdeacon grew up in Hamilton, Ohio, and now resides in the West Side of Cincinnati, Ohio.
Professor , COM EH Indstr Hygiene Bhattacharya Lab
138 Kettering Lab Complex
Dr. Amit Bhattacharya holds a Ph.D. degree in biomedical/mechanical engineering and a M.S. in fluid mechanics/heat transfer, both from the University of Kentucky in Lexington, Kentucky, U.S.A. He is a tenured Professor of Environmental Health & have also a professor in Biomedical Engineering & Mechanical Engineering at the University of Cincinnati, Cincinnati, Ohio, U.S.A. He is the founding Director of the Biomechanics‑Ergonomics Research Laboratories of the Department of Environmental Health. He is also the founding director of the Occupational Ergonomics/Safety graduate education program and the Pilot Research Training program sponsored by the National Institute for Occupational Safety and Health (NIOSH) and housed in the Department of Environmental Health within college of medicine of the University of Cincinnati. His recent research activities include topics of gene-environment interaction and its impact on human neuromuscular system and application of Nano-sensors/BIOMEMS technology for early detection of neurodegenerative and degenerative skeletal disorders. Over the years, Dr. Bhattacharya’s research at the University of Cincinnati has been sponsored by federal agencies and private organizations (cumulative funding as P.I. and Co-Investigator: ~$29.0 million). Dr. Bhattacharya has made significant contributions in the areas of biomechanics of slips/falls in the workplace, heat stress, occupational biomechanics of repetitive trauma, work station design, physiological/biomechanical effects of external vibration on animals and humans, therapeutic aspects of whole‑body vibration, development of countermeasures for cardiovascular deconditioning resulting from weightlessness, and the development of noninvasive, sensitive techniques for the quantification of postural imbalance as an indicator of neurotoxicity and identification of preclinical biomechanical parameters of osteoarthritis and osteoporosis. His research in the area of noninvasive quantification of postural balance for use in detecting chemical toxicity received national recognition when he was invited by the National Institute of Environmental Health Sciences (NIEHS) to present a hands‑on demonstration of this technique during National Medical Research Day at the U.S. House of Representatives and Earth‑Tech Show (both in Washington, D.C.). Dr. Bhattacharya serves on the editorial board of the Journal of Occupational Ergonomics and was Chairperson of the Safety and Occupational Health Study Section for the National Institute for Occupational Safety and Health (NIOSH). He is frequently invited to serve as ad hoc member on a variety of scientific review panels organized by U.S. National Academies of Sciences & Engineering, National Institute of Health (NIH), NIOSH, CDC and international organizations. Dr. Bhattacharya has been active as an ergonomic/biomechanics consultant to various private industries as well as governmental agencies such as NIOSH and the National Aeronautics and Space Administration (NASA). He is a Fellow of the Biomedical Engineering Society & Charter member of the National Academy of Inventors. Also, he is a full member of the, Human Factors & Ergonomic Society, and the American Industrial Hygiene Association.
Amit Bhattacharya’s current Translational Research activities resulting in a Medical Device and a start up Biomedical company
Dr. Bhattacharya’s current research activities include: 1) impact of environmental toxicants (e.g. Mn) on human neuromuscular system and susceptibility of developing degenerative skeletal disorder (e.g. Pb induced osteoporosis),&nb
Ohio Regents Eminent Scholar Chaired Professor of Aerospace Engineering; Professor of Otolaryngology , CEAS - Aerospace Eng
799 Rhodes Hall
- Gas Turbines for Power Generation and Propulsion Systems
- Experimental Fluid Mechanics
- Combustion Control
- Heat Transfer
- Rocket and Airbreathing Propulsion
- Plume Characteristics
- Fire Suppression
- Oil-well Drilling Hydrodynamics
Assistant Professor of Chemical Engineering , CEAS - Chemical Eng
846 Engineering Research Cntr
The lab’s research interests broadly include peripheral nerve and spinal cord injuries, cell-extracellular matrix interactions, biomaterials, and all facets of tissue engineering. This research area is a highly interdisciplinary field integrating many specialties such as engineering, chemistry, and biology. Our studies aim to systematically examine injury and disease states, and use engineering tools to understand and build viable clinical solutions.
Assistant Professor , COM IM Cardiology Division
3939 Cardiovascular Rsrch Cntr
Kevin Haworth’s research interests broadly include biomedical ultrasound imaging and therapy. In particular, he is currently directing and conducting research in medical ultrasound including the use of bubbles for diagnostic and therapeutic applications. His work includes studies of cavitation imaging and acoustic droplet vaporization for gas scavenging and imaging. These studies have been funded through the National Institutes of Health, the American Heart Association, and institutional awards. Ongoing studies of passive cavitation imaging are being pursued to develop image-guidance for cavitation-based therapies such as drug delivery and thrombolysis. Additional studies are being performed to modify the imaging algorithm for improved image quality. Dr. Haworth is the principal investigator of an NIH-NHLBI K25 grant entitled "Ultrasound-mediated oxygen scavenging for inhibition of reperfusion injury.” While new therapies to restore blood flow during myocardial infarction (i.e., a heart attack) can be life-saving, up to half of the volume of heart tissue at risk during a heart attack dies, paradoxically, due to the return of blood flow. The previously oxygen-started heart muscle responds to the influx of oxygen by creating free radicals that damage the patient’s heart cells, so-called reperfusion injury. This project uses a novel, ultrasound-mediated technique to sequester oxygen from the blood to limit free radical formation and reduce reperfusion injury.
Professor of Internal Medicine, Division of Cardiovascular Diseases; Professor of Biomedical Engineering; Director, Image-Guided Ultrasound Therapeutics Laboratories; Scientific Director, Heart, Lung, and Vascular Institute , COM IM Cardiology Division
3935 Cardiovascular Rsrch Cntr
Professor , COM Ophthalmology
Graduate Program Director and Associate Professor , COM EH Bio Meller Lab
316 Kettering Lab Complex
Dr. Meller and his group have developed a number of successful methods for the prediction of protein structure, protein-protein interactions and functional hot spots in proteins (Adamczak et al., 2004, 2005; Wagner et al., 2005; Porollo and Meller, 2007, 2010; Adamczak et al., 2011; Phatak et al., 2011). Several web servers developed by the group, including Sable, Sppider, Minnou and Polyview have widely been used, with a total of over 900,000 submissions from more than 30,000 users in many countries. For the development of successful prediction, modeling and visualization tools for structural bioinformatics and functional genomics, Dr. Meller received Ohio Cyber-infrastructure Experimental & Application Research Award. Dr. Meller has also been active in the development and applications of methods for knowledge extraction from high dimensional genomic data (Sinha and Meller, 2008; Shinde et al., 2010; Huang et al., 2012).
Benefiting from a strong emphasis on team science at the University of Cincinnati and Cincinnati Children’s Hospital Medical Center, Dr. Meller and his group have also been involved in many collaborative projects with direct medical relevance. Examples of such interdisciplinary efforts include sequencing and annotation of human pathogens, identification of markers associated with disease subtypes in cancer and autoimmunity, modeling of signal transduction pathways in differentiation and development, developing inhibitors of critical protein-protein interactions in autophagy, bone marrow transplants, and pathogen-host interactions.
Dr. Meller has been broadly involved in quantitative and computational training efforts within UC College of Medicine and College of Engineering and Applied Sciences, leading several inter-departmental and inter-collegiate initiatives in this regard. Dr. Meller serves as the Director of the newly created PhD program in Biomedical Informatics at UC, co-director of the Biomedical Informatics Graduate Certificate Program, and has been involved in several informatics and quantitative training efforts at UC College of Medicine, including T32 Advanced Multidisciplinary Training Program for Systems Biology and T32 Gene-Environment Interactions Training Grant. In addition, Dr. Meller is the co-director of the Bioinformatics Core for the Center of Environmental Genetics at the University of Cincinnati. He also serves as the director of Protein Informatics Core at Cincinnati Children’s Hospital Medical Center.
Associate Professor of Molecular & Cellular Physiology , COM Physiology Pixley Lab
4206A Medical Sciences Building
Research in the Pixley lab has moved from a past emphasis on the neurogenesis and neuropharmacology of the olfactory system into more applied neural tissue repair work. Our current focus is on using novel biomaterials to promote neural tissue repair and regeneration. One of the most promising biomaterials is magnesium, primarily in metal form. Magnesium metal has properties that have increasingly attracted attention in recent years for use as a bioresorbable biomedical implant material. The most advanced uses are currently as bone fixation devices and as a cardiovascular stent material. Magnesium metal is strong initially, then very safely resorbs into the body. We are identifying novel ways to use magnesium metal to improve recovery of nervous tissues from injury damage, focusing first on repairing injury cuts in peripheral nerves in rats. We are also exploring the use of ionic magnesium for nervous tissue repair. Magnesium in ionic form is known to be neuroprotective and aids recovery of brain tissues after traumatic injury or stroke. Magnesium ions reduce secondary neuronal damage that occurs after the initial injury and reduce vasospasm that occurs in the brain after damage and is also damagine. Our collaborative group includes surgeons, neurobiologists, neuropathologists, and engineers from many categories. We are currently funded by an NSF grant that supports an Engineering Research Center dedicated to Revolutionizing Metallic Biomaterials (http://erc.ncat.edu/). As a second focus, the lab is exploring the use of carbon nanotube (CNT) materials for nervous tissue repair. Expert engineering groups at UC produce novel forms of CNT materials, which are linear biomaterials with promise for promoting neuronal outgrowth and repair. Our initial work shows that neuronal stem cells migrate readily along CNT thread and complete differentiation. We are also using CNT materials to guide nervous tissue repair.