Bioresponsive lab diagram and imaging

Bioresponsive Materials Lab

Our lab seeks to develop biomaterial and therapeutic delivery systems that specifically respond to cell-generated signals. These next-generation, "smart" material systems enable us to engineer comprehensive regeneration of damaged or diseased tissues


Specific applications for these healing-responsive technologies include:

  • Large-scale regeneration of orthopedic injuries or defects
  • Healing of chronic skin wounds
  • Elimination of dental implant infections

Currently seeking talented and motivated students from a broad range of disciplines - apply today!

Contact Us

The Bioresponsive Materials Lab is located in room 549 in the Engineering Research Center (ERC) at the University of Cincinnati in Cincinnati, OH.

828 Engineering Research Center
2901 Woodside Dr
Cincinnati, OH 45221

Follow us on Twitter! @MartinLab_UC

Faculty & Principal Investigator

Headshot of John Robert Martin

John Robert Martin

Assistant Professor, CEAS - Biomedical Eng



John R. Martin is an assistant professor in the Department of Biomedical Engineering in the College of Engineering and Applied Science at the University of Cincinnati. Dr. Martin completed his undergraduate degree at the University of Kentucky where he majored in Biosystems Engineering before obtaining a Ph.D. in Biomedical Engineering at Vanderbilt University investigating cell-degradable tissue engineering scaffolds. Following his doctoral work, he completed a postdoctoral fellowship at the Massachusetts Institute of Technology in the Department of Chemical Engineering where he researched drug delivery systems for the regeneration of craniofacial bone tissue.
Dr. Martin leads the Bioresponsive Materials Lab at UC, exploring “smart” biomaterial systems that leverage precise cell-generated signals (including reactive oxygen species and enzymatic activity) to activate biomaterial functionality and guide tissue regeneration. This interdisciplinary research integrates polymer science and materials engineering alongside pharmacology and biology to build new systems for regenerating orthopedic injuries in the clinic.