Barrile Research Laboratory of Personalized Bioengineering

The Barrile Lab aims to elucidates molecular mechanisms of cell-cell and cell-microenvironment interactions that govern organ functions during the homeostasis and disease state, and how these processes can be therapeutically targeted in order to create personalized treatment strategies for complex human disorders.

In our Lab, we combine principles of stem cell biology with tissue engineering techniques to generate personalized in vitro models of human tissues and organs designed to recapitulate key aspects of human pathologies not captured by conventional pre-clinical models.