Long-term dose-controllable drug delivery

Current efforts in the area of ocular drug delivery include frequent intravitreal injections, which is not only invasive and inconvenient for patients but also may increase the risk of complications. Therefore, development of stable drug delivery systems which have ability to be released in a controlled manner for the long term is necessary.

This research project is about developing dose-controllable implants, which release drug on-demand, and determining drug release kinetics. Drug inside the implant capsule made of biodegradable polymer is released upon exposure to light. During the summer, you will have experience on developing polymer capsules and examining characteristics of drug delivery.

The advisor will provide basic principles in soft materials, drug delivery, and various analytical technique.

Basic chemistry lab experience is required.

Diagram of drug delivery

Figure. Implant that releases drug through nanopores.

Director

Headshot of Yoonjee   Park

Yoonjee Park

Assoc Professor, CEAS - Chemical Eng

584 MANTEI

513-556-1359